
Tinospora Crispa: Thai Traditional Immune Support Herb for Natural Wellness and Pain Relief
Medically Reviewed by Dr. Sarah Chen, ND, AHG
Dr. Sarah Chen is a licensed naturopathic physician with advanced certification in Traditional Thai Medicine and Western herbal therapy. With over 15 years of clinical experience, she specializes in evidence-based herbal pain management and integrative approaches to chronic inflammatory conditions.
Professional Credentials:
- Doctor of Naturopathic Medicine (ND), Bastyr University
- Professional Member, American Herbalists Guild (AHG)
- Board Certified in Botanical Medicine, AANP
- Licensed Naturopathic Physician, Washington State
- Member, American Botanical Council Advisory Board

Tinospora crispa, commonly known as Boraphet, is a revered herb in Thai traditional medicine, celebrated for its immune-supporting properties. This article delves into the various aspects of Tinospora crispa, including its botanical characteristics, potential health benefits, and scientific backing. Readers will gain insights into how research suggests this herb may enhance wellness and provide natural pain relief. Many individuals seek effective, natural solutions for immune support and overall health, and Tinospora crispa offers a promising option. We will explore its role in traditional medicine, the scientific research supporting its benefits, and how it is incorporated into products like Tapee Tea.
⚠️ Medical Disclaimer: This article provides educational information about natural health approaches and should not replace professional medical advice. Always consult a qualified healthcare provider before starting any herbal supplement, especially if you have existing health conditions or take medications.
Indeed, extensive research highlights the diverse traditional and pharmacological benefits of Tinospora crispa, extending beyond just immune support. For more in-depth scientific studies, you can explore resources like PubMed research on Tinospora crispa.
Tinospora Crispa: Ethnomedicinal Uses, Immunomodulatory & Analgesic Benefits
Tinospora crispa(L.) Hook. f. & Thomson (Menispermaceae) is a plant indigenous to Africa and South-East Asia. It is widely used in ethnomedicine to alleviate various diseases including hypertension, diabetes, rheumatism, jaundice, inflammation, fever, fractures, scabies, and urinary disorders. Numerous in vitro and in vivo investigations have already established the antidiabetic, anticancer, antiparasitic, antimicrobial, immunomodulatory, hepatoprotective, analgesic, antipyretic, antihyperuricemic, and pesticidal activity of this plant, as well as its effects on the cardiac and the central nervous system.
An updated and comprehensive review on the ethnomedicinal uses, phytochemistry, pharmacological activity and toxicological profile of Tinospora crispa (L.) Hook. f …, MS Bari, 2023
What is Tinospora Crispa in Thai Traditional Medicine?
Tinospora crispa is a climbing shrub native to Southeast Asia, particularly Thailand, where it has been used for centuries in traditional medicine. Known for its bitter taste, it is often utilized in herbal remedies aimed at enhancing health and vitality. The herb is recognized for its potential to support immune function and promote overall wellness, with preliminary evidence showing promising results. Its historical significance in Thai medicine is profound, as it has been employed to treat various ailments, including fevers and infections. For further exploration of traditional Thai medicinal practices, consider resources like PubMed research on Traditional Thai Medicine.
What are the botanical characteristics and common names of Tinospora Crispa?
Tinospora crispa is characterized by its green, slender, often angular stems and heart-shaped leaves. The plant can grow up to 10 meters long, often climbing on other vegetation for support. Common names for Tinospora crispa include “Boraphet” in Thai and “Giloy” or “Guduchi” in India. It is found in tropical and subtropical climates, thriving in well-drained soils. The plant‘s unique morphology and adaptability contribute to its widespread use in traditional herbal practices.
How Does Tinospora Crispa Support Immune Health?
Tinospora crispa is renowned for its immunomodulatory effects, which research suggests help regulate the immune system‘s response to pathogens. The herb contains various bioactive compounds that contribute to its potential health benefits, making it a valuable addition to natural wellness regimens.
What immunomodulatory and anti-inflammatory properties does Tinospora Crispa have?
Research suggests the immunomodulatory properties of Tinospora crispa are primarily attributed to its active compounds, such as alkaloids, diterpenoid lactones, and glycosides. These compounds have been shown to enhance the activity of immune cells, promoting a balanced immune response. Additionally, studies indicate Tinospora crispa exhibits anti-inflammatory properties, which may help reduce inflammation in the body, further supporting immune health. Research indicates that these mechanisms may help the body combat infections more effectively.
Studies have further elucidated the specific ways Tinospora crispa modulates the immune system, demonstrating its ability to stimulate key immune markers.
Tinospora Crispa: Traditional Immune System Modulator
Immunomodulators are substances that modify immune system response to a threat. Immunomodulators modulate and potentiate the immune system, keeping it highly prepared for any threat. The immunomodulatory effect of the traditional medicineTinospora crispais investigated in this work. The results of this study obviously indicate thatT. crispahas immunomodulatory effects through the stimulation of INF-γ, IL-6, and IL-8 expressions.
Immunomodulatory effect of an isolated fraction from Tinospora crispa on intracellular expression of INF-γ, IL-6 and IL-8, WN Abood, 2014
What Scientific Research Supports Tinospora Crispa’s Immune Benefits?
Numerous studies have investigated the potential health benefits of Tinospora crispa, highlighting its potential as a natural immune booster. The scientific community is increasingly recognizing the importance of traditional herbs in modern health practices.
Which bioactive compounds in Tinospora Crispa contribute to immunity?
The primary bioactive compounds in Tinospora crispa include tinosporaside, berberine, and various flavonoids. These compounds have been shown to possess antioxidant and anti-inflammatory properties, which research suggests are crucial for maintaining immune health. Their synergistic effects may enhance the body’s ability to fight off infections and support overall wellness.
Further research into the herb‘s mechanisms reveals its capacity to influence pro-inflammatory mediators, offering insights into its traditional use for inflammatory conditions.
Tinospora Crispa: Traditional Anti-Inflammatory & Immune Support
Immunomodulatory effects ofTinospora crispahave been investigated due to its traditional use to treat several inflammatory disorders associated to the immune system. The present study reports the underlying mechanisms involved in the stimulation of 80% ethanol extract ofT. crispastems on pro-inflammatory mediators release in lipopolysaccharide (LPS)-primed U937 human macrophages via MyD88-dependent pathways. The results suggested thatT. crispaextract stimulated the MyD88-dependent signaling pathways by upregulating the various immune inflammatory related parameters.
Standardized ethanol extract of Tinospora crispa upregulates pro-inflammatory mediators release in LPS-primed U937 human macrophages through stimulation of …, MA Haque, 2020
What do recent clinical trials reveal about Tinospora Crispa’s efficacy and safety?
While preclinical studies and some small clinical trials suggest that Tinospora crispa may enhance immune function and reduce inflammation, large-scale, well-controlled clinical trials are limited. Available evidence indicates that the herb is generally safe for consumption when used appropriately, with minimal side effects reported. However, more rigorous research is needed to fully establish its efficacy and safety profile.
How Does Tapee Tea Harness Tinospora Crispa for Natural Pain Relief and Wellness?

Tapee Tea is an herbal blend that incorporates Tinospora crispa, leveraging its potential health benefits to promote natural pain relief and overall wellness. This unique formulation is designed to provide a holistic approach to health, combining the properties of various herbs.
What role does Tinospora Crispa play in the Tapee Tea herbal blend?
In the Tapee Tea blend, Tinospora crispa serves as a key ingredient known for its immune-boosting and anti-inflammatory properties. The inclusion of this herb enhances the tea‘s effectiveness in promoting wellness and alleviating discomfort. Users often report improved overall health and vitality when incorporating Tapee Tea into their daily routine, though individual results may vary.
How does Tapee Tea ensure authenticity, purity, and ethical sourcing?
TeaTapee.com prioritizes authenticity and quality in its products. The company sources its Tinospora crispa and other herbal ingredients from trusted suppliers who adhere to ethical and sustainable practices. Each batch of Tapee Tea undergoes rigorous lab testing to ensure purity and potency, providing consumers with confidence in their herbal choices.
What Are Traditional and Modern Uses of Boraphet Beyond Immunity?

Boraphet, or Tinospora crispa, has a rich history of use in traditional medicine, extending beyond immune support. Its versatility makes it a valuable herb in various health applications. For broader information on Asian herbal medicine, databases like NCBI’s resources on Traditional Asian Medicine can be helpful.
How is Boraphet used for natural pain relief and antioxidant support?
In addition to its immune-boosting properties, Boraphet is traditionally used for its analgesic effects, with some preliminary evidence suggesting it may help alleviate pain associated with various conditions. The herb‘s antioxidant properties also contribute to its ability to combat oxidative stress, which research suggests promotes overall health and longevity. Many users find relief from mild pain and inflammation through the regular consumption of Tinospora crispa, although clinical evidence is limited and more rigorous studies are needed.
What are common usage guidelines and precautions for Tinospora Crispa?
When using Tinospora crispa, it is essential to follow recommended dosage guidelines to ensure safety and efficacy. Generally, a daily intake of 300 mg to 1,000 mg of standardized extract is considered safe for most individuals. However, those with specific health conditions, pregnant or breastfeeding women should consult a healthcare professional before use. Awareness of potential allergies to related plants is also crucial.
Safety Information and Precautions for Tinospora Crispa
While Tinospora crispa is generally considered safe for most individuals when used appropriately, it’s crucial to be aware of potential interactions, contraindications, and when to seek professional medical advice.
Potential Drug Interactions
- Immunosuppressants: As Tinospora crispa is known for its immunomodulatory effects, it may theoretically interact with immunosuppressant medications, potentially reducing their effectiveness.
- Antidiabetic Medications: Some studies suggest Tinospora crispa may lower blood sugar levels. Combining it with antidiabetic drugs could lead to hypoglycemia (low blood sugar).
- Anticoagulants/Antiplatelet Drugs: There is limited evidence, but some traditional uses suggest effects on blood clotting. Caution is advised if taking blood thinners.
- Other Herbs/Supplements: Be cautious when combining Tinospora crispa with other herbs that have similar effects (e.g., immune-boosting, blood sugar-lowering, or anti-inflammatory) to avoid additive effects.
Contraindications and Side Effects
- Pregnancy and Breastfeeding: Due to a lack of sufficient safety data, Tinospora crispa is generally not recommended for pregnant or breastfeeding women.
- Autoimmune Diseases: Individuals with autoimmune conditions (e.g., rheumatoid arthritis, lupus, multiple sclerosis) should exercise caution due to the herb’s immunomodulatory properties, as it could potentially stimulate the immune system.
- Surgery: Discontinue use at least two weeks before any scheduled surgery due to potential effects on blood sugar and clotting.
- Common Side Effects: Mild side effects may include gastrointestinal upset (nausea, constipation, diarrhea) or allergic reactions in sensitive individuals.
When to Consult a Healthcare Professional
Always consult a qualified healthcare provider before starting any new herbal supplement, especially if you:
- Have any pre-existing medical conditions (e.g., diabetes, autoimmune disorders, liver disease).
- Are taking any prescription medications or other supplements.
- Are pregnant, planning to become pregnant, or breastfeeding.
- Experience any adverse reactions or unusual symptoms after taking Tinospora crispa.
- Are unsure about the correct dosage or duration of use.
How Can You Identify and Buy Authentic Thai Herbal Products Like Tapee Tea?
With the growing popularity of herbal products, it is vital to know how to identify authentic Thai herbal teas to ensure quality and effectiveness.
What certifications and lab tests verify genuine Tinospora Crispa products?
Authentic Tinospora crispa products should be accompanied by certifications from recognized health authorities or third-party organizations, indicating that they have undergone rigorous testing for quality and safety. Look for products that provide lab test results confirming the presence of active compounds and the absence of contaminants. This transparency is essential for consumer trust.
Why is ethical and sustainable sourcing important for Thai herbal teas?
Ethical and sustainable sourcing practices are crucial for preserving the environment and supporting local communities. By choosing products from companies that prioritize these practices, consumers can contribute to the well-being of both the planet and the people involved in herbal cultivation. This commitment to sustainability ensures that future generations can continue to benefit from these valuable herbs.

